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Intraocular lymphomas (i-OL) are rare and aggressive subsets of primary cerebral tumors. Little is known about the pathogenesis. This is explained by the scarcity of patients and the tiny amount of ocular fluid sampled for biological analyses. In most cases, i-OL is misdiagnosed because its clinical features can mimic other ocular conditions. To date, no independent biological tool is able to firmly diagnose i-OL; the combination of cytologic examination, immunochemistry, flow cytometry, and molecular analysis is required.
Read more: ISOLD: A New Highly Sensitive Interleukin Score for Intraocular Lymphoma Diagnosis
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Intraocular pressure, the only modifiable risk factor for glaucoma, is traditionally lowered with topical medication, laser or invasive surgery.1,2 More recently, there has been increased interest in alternative methods for lowering intraocular pressure through the use of minimally invasive extraocular drug delivery implants, such as punctual plugs, as well as more invasive surgical implants or intraocular injectable medication depots. The main goal of these alternative methods of drug delivery is to supplant the need for daily topical medication instillation that is associated with side effects and poor adherence.
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To review the role of anatomic endpoints in clinical trials for the study of nonexudative age-related macular degeneration (AMD) with an emphasis on a novel composite endpoint for the study of emerging therapies for intermediate AMD (iAMD).
Read more: Anatomic Clinical Trial Endpoints for Nonexudative Age-Related Macular Degeneration
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To provide visual and anatomic outcomes for patients with retinal detachment (RD) in whom primary pneumatic retinopexy (PR) failed.
Read more: Outcomes after Failed Pneumatic Retinopexy for Retinal Detachment
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To examine the impact of topical corticosteroid use after the start of antiamoebic therapy (AAT) on the outcomes of Acanthamoeba keratitis (AK) therapy.
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Although primary congenital glaucoma (PCG) is a rare disease, it occurs worldwide. Surgery is the mainstay of treatment of PCG, with surgical success rates having improved dramatically over the past few decades to 70% to 80%.1 However, there are few reports of patient-reported outcomes in PCG.2,3 A diagnosis of a sight-threatening condition such as PCG in a newborn or very young child can have significant psychosocial implications for families, who may experience a range of emotions such as guilt, fear, sadness, anxiety, and grief.