AAO Journal Archive
- Classification of Vitreous Seeds in Retinoblastoma
- Topical 5-Fluorouracil 1% as Primary Treatment for Ocular Surface Squamous Neoplasia
- Individualized Stabilization Criteria–Driven Ranibizumab versus Laser in Branch Retinal Vein Occlusion
- Correlation of Histologic Features with In Vivo Imaging of Reticular Pseudodrusen
- Pseudodrusen and Incidence of Late Age-Related Macular Degeneration in Fellow Eyes in the Comparison of Age-Related Macular Degeneration Treatments Trials
- Pharmacotherapies for Retinal Detachment
- Can Automated Imaging for Optic Disc and Retinal Nerve Fiber Layer Analysis Aid Glaucoma Detection?
- Suture Colonization Rate in Adjustable Strabismus Surgery
- Genetic and Dietary Factors Influencing the Progression of Nuclear Cataract
- Diagnostic Accuracy of Optical Coherence Tomography and Scanning Laser Tomography for Identifying Glaucoma in Myopic Eyes
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Joachim y otros (p. 2482) evaluaron la incidencia y progresión de la degeneración macular relacionada con la edad (AMD) durante un período de 15 años en 3.654 adultos de 49 años o más que participaron en el Estudio Oftalmológico Blue Mountain (Blue Mountain Eye Study). Los investigadores encontraron una incidencia global de 22,7% para AMD temprana y 6,8% para AMD tardía. Después de hacer los ajustes para riesgos competitivos, la incidencia de AMD temprana y tardía fue de 15,1% y 4,1%, respectivamente; después de una mayor estandarización de edades con la población del Estudio Oftalmológico Beaver Dam (Beaver Dam Eye Study), la incidencia temprana y tardía fue de 13,1% y 3,3%, respectivamente.
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A 51-year-old man had a lesion of the right lower eyelid (Fig 1), present for a year, surgically removed. Histopathology revealed a rare pilosebaceous hybrid cyst lined by 2 distinctive cell types: a bilayer epithelium of ductal origin (Fig 2, bold arrows) and keratinized stratified epithelium of infundibular origin (Fig 2, thin arrows). Most pilosebaceous cysts, in contrast, are composed of components from a single portion of the pilosebaceous complex. The different types of cutaneous cysts are shown in the diagram (Fig 3).
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A 15-year-old boy presented with immediate vision loss after his left eye struck a rock during a fall. There were no signs of globe rupture. Ophthalmoscopy demonstrated a central retinal artery occlusion. The area of the optic nerve head was excavated and filled with hemorrhage with blood emanating into the vitreous and a ring of peripapillary hemorrhage (Fig 1). Computed tomography (Fig 2) showed orbital fat-stranding around the nerve with a linear hypodensity (arrow) near its attachment to the globe.
Read more: Optic Nerve Head Avulsion: Clinical, Radiographic, and Sonographic Correlations
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Joachim (p. 2482) 等对参与蓝山眼病研究 (Blue Mountain Eye Study) 的3654名49岁及以上成人进行为期15年的年龄相关性黄斑变性 (age-related macular degeneration [AMD]) 疾病起病和进展观察。研究者发现早期AMD总体发病率为22.7%, 晚期AMD总体发病率为6.8%。校正相关危险因素后, 早期和晚期AMD发病率分别为15.1%和4.1%; 进一步以Beaver Dam眼病研究人群为参照进行年龄标准化, 得到早期和晚期AMD发病率分别为13.1%和3.3%。就进展风险而言, 早期AMD病变的严重程度是进展为晚期AMD的重要预测因素。女性、风险等位基因CFH-rs1061170及ARMS2-rs10490924的并存是早期AMD发病的独立危险因素; 当前吸烟史和至少存在1个风险等位基因与晚期AMD发病相关。