AAO Journal Archive
- Classification of Vitreous Seeds in Retinoblastoma
- Topical 5-Fluorouracil 1% as Primary Treatment for Ocular Surface Squamous Neoplasia
- Individualized Stabilization Criteria–Driven Ranibizumab versus Laser in Branch Retinal Vein Occlusion
- Correlation of Histologic Features with In Vivo Imaging of Reticular Pseudodrusen
- Pseudodrusen and Incidence of Late Age-Related Macular Degeneration in Fellow Eyes in the Comparison of Age-Related Macular Degeneration Treatments Trials
- Pharmacotherapies for Retinal Detachment
- Can Automated Imaging for Optic Disc and Retinal Nerve Fiber Layer Analysis Aid Glaucoma Detection?
- Suture Colonization Rate in Adjustable Strabismus Surgery
- Genetic and Dietary Factors Influencing the Progression of Nuclear Cataract
- Diagnostic Accuracy of Optical Coherence Tomography and Scanning Laser Tomography for Identifying Glaucoma in Myopic Eyes
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Mimoun et al1 were first to describe a peculiar yellowish pattern in patients with age-related macular degeneration (AMD) as reticular pseudodrusen (RPD) in 1990. Since that time, improved identification and clinical descriptions of RPD and their dynamic nature have become possible with the development of newer imaging modalities including infrared and spectral domain optical coherence tomography (SD OCT) imaging. By most investigators, RPD are considered to be associated with or at least have some developmental relationship to subretinal drusenoid deposits, which have been identified histopathologically as residing internal to the retinal pigment epithelium.
Read more: The Relationship Between Reticular Pseudodrusen and Severity of AMD
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To determine the extent of geographic variation in the proportion of patients with newly diagnosed open-angle glaucoma (OAG) undergoing visual field (VF) testing, fundus photography (FP), and other ocular imaging (OOI) among patients residing in different US communities.
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To describe the natural history of dry eye disease (DED), which chronically affects millions of people in the United States.
Read more: Long-term Natural History of Dry Eye Disease from the Patient's Perspective
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To investigate the characteristics of optic disc rotation and ocular parameters affecting optic disc rotation in healthy myopic eyes.
Read more: Characteristics of Optic Disc Rotation in Myopic Eyes
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Leber hereditary optic neuropathy (LHON) is a disorder characterized by severe and rapidly progressive visual loss when caused by a mutation in the mitochondrial gene encoding NADH:ubiquinone oxidoreductase subunit 4 (ND4). We have initiated a gene therapy trial to determine the safety and tolerability of escalated doses of an adeno-associated virus vector (AAV) expressing a normal ND4 complementary DNA in patients with a G to A mutation at nucleotide 11778 of the mitochondrial genome.
Read more: Gene Therapy for Leber Hereditary Optic Neuropathy