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To investigate the effect of the severity of corneal guttae on quality of vision (QOV) in patients with mild Fuchs' endothelial corneal dystrophy (FECD).
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Since the landmark study by Spaide et al1 described the enhanced depth imaging mode of spectral-domain optical coherence tomography to visualize the choroid, choroidal thickness has been examined intensively in recent investigations. None of the preceding studies examined whether neurologic diseases were associated with an abnormal choroidal thickness, although the choroidal blood vessels predominantly influencing choroidal thickness can be regarded as an extracranial part of the intracranial cerebral vascular system.
Read more: Cognitive Function and Subfoveal Choroidal Thickness: The Beijing Eye Study
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The ophthalmic examination of infants and children is often challenging owing to reduced cooperation; however, it is indispensable to make reliable diagnoses and prevent amblyopia and loss of vision. In this context, examination under general anesthesia is often required.
Read more: Intraoperative Optical Coherence Tomography in Children with Anterior Segment Anomalies
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Recent advances in ultra-widefield imaging that allow generation of high-definition, 3-dimensional representations of the fundus are redefining our approach to quantification of retinal diseases. The clinical relevance of these advances as illustrated by Sagong et al in their article entitled, “Assessment of Accuracy and Precision of Quantification of Ultra-widefield Images” is in establishing the tools required to define retinal pathology.1,2 Ideally, for a new metric to carry substantial value, it would facilitate ≥1 of the following criteria: meaningful quantification of disease severity, prediction of disease progression, and/or prediction of treatment response.
Read more: Not All Retina Is Created Equal: Metabolic Quantification of Ultra-Widefield Images
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To review the available evidence on the effectiveness of prophylactic topical nonsteroidal anti-inflammatory drugs (NSAIDs) in preventing vision loss resulting from cystoid macular edema (CME) after cataract surgery.
Read more: Topical Nonsteroidal Anti-inflammatory Drugs and Cataract Surgery
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Orbital inflammatory diseases (OIDs) from various causes may have a similar clinical presentation, with orbital biopsy being a key investigation to assist with diagnosis. Granulomatosis with polyangiitis (GPA) is an idiopathic granulomatous inflammatory disease that forms part of the spectrum of antineutrophil cytoplasm antibody (ANCA)-associated vasculitis. When left untreated, GPA is an aggressive disease, can result in severe, permanent organ damage, and is potentially life threatening when vital organs are affected.