Saksens et al1 reported the clinical characteristics and long-term follow-up of dominant cystoid macular dystrophy (DCMD). They identified the association of high axial hyperopia with intraretinal cystoid macular fluid collections (CFC) and implicated a primary dysfunction of Muller cells and/or the retinal pigment epithelium as the cause of CFC. An alternate explanation of the pathophysiology may involve a thick choroid that may occur in hyperopia.2 Increased choroidal thickness may result in increased osmotic pressure causing secondary leakage into the retina via the relatively weak blood–retinal barrier at the optic disc margin.


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